If, when sending e-mails, you still think casting a wide, generic net will yield a low, although productive, rate of return, think again. Why? People like Chris Anderson, editor in chief of Wired magazine, finally have had enough, and they're taking action. Says Anderson: "I only want two kinds of e-mail – those from people I know and those from people who have taken the time to find out what I'm interested in and (have) composed a note meant to appeal to that." His advice is to trim what e-mail you actually open, even from regulars. And if your time is wasted, ban those contacts forever.